Do Your Genes Make You Fat? With Dr Giles Yeo
Do Your Genes Make You Fat? With Dr Giles Yeo
💬 “People think I’m anti-physics. I’m not anti-physics. Calories don’t give you the information to improve your diet.”
⚡️ Dr Giles Yeo is a geneticist at Cambridge University specialising in obesity and how our brain controls food intake. He’s also the author of ‘Why Calories Don’t Count’ and ‘Gene Eating’.
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For me it's my job. When I work in a all day walking job I'm losing weight. When I'm sat at my desk all day I'm tubbier 😅
Good God. You had a say when you got fat.
It is marvellous to be able to enjoy your smart and interesting ideas and discussion!
Thank you very much, to both dr. Karan and dr. Yeo!
@52:34 correction here: brown rice is the staple for some of the Southern Indian state like Kerala
From observation, it looks like both host and guest have genes that are predisposed to fat accumulation.
They are not the only ones – it took me eating the OMAD way to shed 39 lbs / 18 kgs of total body weight.
That said, it is a daily battle to stay active and not feel hungry and to not, re-pile the weight back on.
For those that do not have this problem, consider yourselves very lucky that your genes are not programmed this way.
If you thought that it was only humans that have this love of food that ends up in some of us being overfat… and under muscled.
In 2016, a study in the journal Cell Metabolism found that Labradors and some closely related Flat Coat retrievers have a specific gene mutation that is absent from other dogs. This gene mutation affects their motivation for food, increases the likelihood of storing fat and makes them more prone to obesity.
This is very true, it is very nuanced and multifactorial. I have been obese since the age of 8. I have finally got to a point where I can at least maintain my weight avoiding wild fluctuations (minus the pandemic).
It's a never ending battle but focusing on what works for YOU will help YOU the most.
answer is No
I think we are all inclined genetically to gain weight, due to our evolution, until the current age we didn't have this much food available all the time, so we had to be able to store the excess energy when we had plenty of food… some ppl might hear that it's genetic and just not try to change their habits, because why do that, they don't have any impact on their genes… And look for easier alternatives like ozempic, for those who can afford it, because therapy and other changes in habits are more expensive…
Throughout my life until my late 30s, I maintained a healthy weight and never faced any issues. I used to believe that those struggling with overweight and obesity simply lacked willpower. However, I realized how misguided that view was when I started taking anxiety medication in my early 40s. By the third year, I experienced rapid weight gain, crossing into the overweight category. Now, I truly understand the challenges of being overweight and the frustration of feeling powerless to change it.
No, not genetics. Maybe in as much as variations of weight, but not obese. Its carbs. Simply by not eating carbs you can lose a lot of weight in little time. I lost 60 pounds in 30 days, by eating zero carbs. ZERO CARBS, as in zero plants. And calories? Irrelevant. I was eating between 2 and 3 times as many calories while I lost the weight.
How does ozempic work if you’re considerably overweight, but, get full very easily?
Hey, Dr Karan. Theres is one topic i think needs to be brought to more attention: I have noticed with medical research, while working in a hospital and university, is that a lot of people manipulate their research in order to suit their narrative. Usually its because they want to prove their point really badly and get published, or sometimes there may be external pressure from the people funding the research. This brings into question wether a lot of the studies out there should be trusted. It seems to be alot more common among allied healthcare professionals (not hating on them as I myself am a neurophysiologist) than actual doctors or medical professionals that work in much more serious settings. Also, although an article may be published, every journal has different standards to accepting articles. This allows studies with much poorer research protocol to get published in lower tier journals and may still show up on research search engines such as Google Scholar/Pubmed/etc.
From there you get these underqualified online health influencers that cherry-pick these studies in order to promote one of their herbal medication that may just be the equivalent to a placebo (I think you did cover something similiar before).
It's the same problem with veggies up here in Scandinavia, boiled to death and no spices. The first time I remember liking vegetables was when we went to a Chinese resturant and my mom ordered some stir-fry, and I thought the vegetables looked so good so got to taste it, and I loved it! Think I was 5/6 years old then. And after that we went to a Chinese resturant for our weekly outing so I could get my stir-fried veggies. 😂
And a few years later, I started cooking myself. I never boil/steam vegetables, only stir-fry, with lots of spices!
Personnellement ce qui m' intrigue comment ce fait- il qu' une fois que 'on a perdu du poids on le reprend aussi vite et même plus…
Pourquoi notre corps veut toujours revenir a notre poids le plus élevé…
There is considerable denial amongst some patient groups about lifestyle, diet and exercise relating to obese presentations.
I definitely have a slow metabolism. It doesn't make sense that I can't lose weight on a low caloric intake and high calorie output. I'm looking forward to starting my stimulant meds for ADHD just for the side effect of increasing my metabolism. I eat balanced, I work out, my job is on my feet and active. Always been on the thicker side since puberty hit,
In my case: idle state give me a devil's appetite.
Love to teddy doc.
I wish some scientists would research into the permanent damage that eating disorders in teenage years does to the body’s metabolism.
Love how genetics, epigentics and social determinants of health are addressed here. In the US social determinants of health account for 80% of health outcomes.
Men of India don't want to understand this concept bcs they could not fat-shame someone and fuel up their superiority complex.
Very few men question this concept like you dr. karan… 😢
Question here:
Do we understand why there is no obesity in other animals. Not the cyclical adaptation of polar bears and such. I mean as a disease like we have. If there is, enlighten me
"85% of open access genetic data from white northern european decent,… a decade ago it was 95%. So we are eating away at it…" that last bit had me in stitches! Esp since the discussion at hand deals with judgments on either how or what we eat
Yeah my genetics make me eat more then my body needs. Your body's caloric needs may differ based on your activity and muscle mass but your still responsible for what you stuff in your mouth. i as a 186cm man can not eat 2000 calories a day "science" bsays i need as i will gain fat. so i don't freaking eat 2000 calories as i don't accept getting fat period. getting fat in 99% of the cases is a CHOICE you made. Don't let anyone tell you diffrent because it fits your weak minded attitude towards overeating.
Your car does not get speed tickets without you pressing the right pedal either. Your choices have consequences.
As for genetics and race. i think thats more to do with what people eat. what if all these groeps eat the same thing for a whole life will there be drastic changes then? black people tend to have more wifes cooking at home from what i see around me. i live in a pretty colored neighborhood and i have all kinds of food smells at al times where my previous white neighbordhood had a ton of food delivery and no food smells at all becasuse they cook less. Restaurants are also mainly white people. so iu thin you cant point at genetics when they are eating vastly diffrent their whole life.
This conversation is making me hungry ! 😇
Without watching, it's more than one thing. I'm an emotional eater. Have been dealing with undiagnosed ASD my entire life, and undiagnosed CPTSD for 15 years. The CPTSD had a huge effect on me, and combined with the CPTSD I started going through periods of binge eating on junk food. When my mental health is good my eating habits are amazing and I can exercise. When my mental health is bad I'm eating junk and not exercising.
These glp1 agonist trials did have control groups who had all the same advice!! Read the study and stop talking off the top of your head!